{"id":17492,"date":"2025-09-03T15:27:16","date_gmt":"2025-09-03T21:27:16","guid":{"rendered":"https:\/\/immunotherapymx.com\/?page_id=17492"},"modified":"2025-11-18T11:53:18","modified_gmt":"2025-11-18T17:53:18","slug":"maria-guadalupe-ramirez-padilla-b-sc","status":"publish","type":"page","link":"https:\/\/immunotherapymx.com\/es\/nuestro-equipo\/maria-guadalupe-ramirez-padilla-b-sc\/","title":{"rendered":"Mar\u00eda Guadalupe Ram\u00edrez Padilla, B.Sc."},"content":{"rendered":"

Especialidad:<\/strong> Modelos precl\u00ednicos, cultivo de c\u00e9lulas de mam\u00edferos e investigaci\u00f3n nutrac\u00e9utica traslacional (Sechium edule<\/em>caseinato de sodio)<\/p>\n\n\n\n

Mar\u00eda Guadalupe Ram\u00edrez Padilla es una bi\u00f3loga centrada en el apoyo experimental a la hematopoyesis\/leucemia, el estr\u00e9s oxidativo y la inflamaci\u00f3n, y los bioactivos derivados de plantas, en particular Sechium edule<\/em> h\u00edbridos. Su experiencia incluye el cultivo in vitro de l\u00edneas celulares hematol\u00f3gicas y de tumores s\u00f3lidos, la manipulaci\u00f3n y dosificaci\u00f3n in vivo en murinos (oral, intraperitoneal, subcut\u00e1nea) y la recopilaci\u00f3n de datos para estudios traslacionales en modelos de lesiones metab\u00f3licas y hep\u00e1ticas. Colabora en proyectos cient\u00edficos del IRM, conectando m\u00e9todos de laboratorio con criterios de valoraci\u00f3n cl\u00ednicamente relevantes.<\/p>\n\n\n\n

\u00c1reas de especializaci\u00f3n<\/h2>\n\n\n\n
    \n
  • Cultivo de c\u00e9lulas de mam\u00edferos (por ejemplo, J774, P388, WEHI-3, 4T1, RAW 264.7, L929, A549, 3T3-L1); ensayos de viabilidad\/proliferaci\u00f3n.<\/li>\n\n\n\n
  • Manipulaci\u00f3n y dosificaci\u00f3n en peque\u00f1os animales en modelos precl\u00ednicos (CD-1, BALB\/c)<\/li>\n\n\n\n
  • Dise\u00f1o y ejecuci\u00f3n experimentales en estudios sobre nutrac\u00e9uticos\/alimentos funcionales (Sechium edule<\/em>marcadores oxidativos e inflamatorios)<\/li>\n\n\n\n
  • Conocimientos b\u00e1sicos de biolog\u00eda molecular y garant\u00eda de calidad (PCR\/dise\u00f1o de cebadores; formaci\u00f3n en sistemas de calidad).<\/li>\n<\/ul>\n\n\n\n

    Educaci\u00f3n<\/h2>\n\n\n\n
      \n
    • Licenciatura en Biolog\u00eda - FES Zaragoza, Universidad Nacional Aut\u00f3noma de M\u00e9xico (UNAM)
      - Examen profesional: Efecto hepatoprotector del extracto h\u00edbrido de Sechium HD-Victor<\/em> (13 de septiembre de 2021)<\/li>\n<\/ul>\n\n\n\n

      Investigaci\u00f3n y experiencia profesional<\/h2>\n\n\n\n
        \n
      • Laboratorio de Hematopoyesis y Leucemia (FES Zaragoza, UNAM) - Apoyo experimental en cultivo celular, manejo de animales y tutor\u00eda de estudiantes (2018-presente).<\/li>\n\n\n\n
      • QuantumLab (Puerto Vallarta, Jalisco) - Bi\u00f3logo de cultivos celulares (Ene 2023-presente)<\/li>\n\n\n\n
      • Zucarmex (Atencingo, Puebla) - Cultivo in vitro de tejidos de ca\u00f1a de az\u00facar (Dic 2021-Ene 2022)<\/li>\n<\/ul>\n\n\n\n

        Proyectos de investigaci\u00f3n<\/h2>\n\n\n\n
          \n
        • PAPIIT IA205222 (UNAM) - Efecto de Sechium edule H387-07 sobre la reducci\u00f3n de la glucosa, la translocaci\u00f3n de GLUT4 y los marcadores oxidativos\/inflamatorios en un modelo de rat\u00f3n diab\u00e9tico.<\/em> (Ene 2022-Dic 2023) - Investigador colaborador<\/li>\n<\/ul>\n\n\n\n

          Certificaciones y formaci\u00f3n t\u00e9cnica<\/h2>\n\n\n\n
            \n
          • Diploma de Biolog\u00eda Molecular - CCBIO (60 h; certificado de competencia DC-3), 2024<\/li>\n\n\n\n
          • Calidad en el Laboratorio Cl\u00ednico: Fundamentos, aplicaci\u00f3n y validaci\u00f3n - CCBIO (20 h), 2024<\/li>\n\n\n\n
          • PCR y dise\u00f1o de cebadores - CCBIO (15 h), 2023<\/li>\n\n\n\n
          • Citometr\u00eda de flujo multicolor - \"Septiembre en Flow\" (12 h), 2022<\/li>\n\n\n\n
          • Beyond the Cell e-Classroom (sorting, single-omics, COVID-19 immune response) - BD\/Bociencias, 2020<\/li>\n<\/ul>\n\n\n\n

            Conferencias y foros cient\u00edficos<\/h2>\n\n\n\n
              \n
            • Congresos de Investigaci\u00f3n FES Zaragoza - Contribuciones orales\/poster (2019, 2021, 2022)<\/li>\n\n\n\n
            • Red de Alimentos Funcionales y Nutrac\u00e9uticos - P\u00f3ster: Actividad hepatoprotectora del h\u00edbrido de chayote HD-Victor<\/em> (Nuevo Vallarta, Nov 2023)<\/li>\n\n\n\n
            • I Encuentro Cient\u00edfico en Medicina Regenerativa (FES Zaragoza) - Ponencia: C\u00e9lulas madre mesenquimales y enfermedades cardiovasculares<\/em> (6 de diciembre de 2024)<\/li>\n<\/ul>\n\n\n\n

              Publicaciones cient\u00edficas destacadas<\/h2>\n\n\n\n
                \n
              1. Hepatoprotective Effect of the Sechium HD-Victor Hybrid Extract in a Carbon-Tetrachloride-Induced Liver-Injury Mouse Model.<\/strong> Biomedicina y Farmacoterapia<\/em> 183:117831 (2025). doi:10.1016\/j.biopha.2025.117831
                - Autores: Santiago-Osorio E., Ram\u00edrez-Padilla M.G.<\/strong>, Cadena-\u00cd\u00f1iguez J., Rosado-P\u00e9rez J., et al.<\/li>\n\n\n\n
              2. Mejora de la Supervivencia de Ratones Leuc\u00e9micos Tratados con Caseinato de Sodio en Combinaci\u00f3n con Daunorubicina sin Toxicidad.<\/strong> Revista de Oncolog\u00eda<\/em> 2021:6635650 (2021). doi:10.1155\/2021\/6635650
                - Autores: Agui\u00f1iga-S\u00e1nchez I., Mel\u00e9ndez-Ibarra F.M., Ledesma-Mart\u00ednez E., Weiss-Steider B., Fajardo-Ordu\u00f1a G.R., Rangel-Corona R., Ram\u00edrez-Padilla M.G.<\/strong>, Santiago-Osorio E.<\/strong>y otros.<\/li>\n<\/ol>\n\n\n\n

                <\/p>","protected":false},"excerpt":{"rendered":"

                Specialty: Preclinical models, mammalian cell culture, and translational nutraceutical research (Sechium edule, sodium caseinate) Mar\u00eda Guadalupe Ram\u00edrez Padilla is a biologist focused on experimental support for hematopoiesis\/leukemia, oxidative stress and inflammation, and plant-derived bioactives\u2014particularly Sechium edule hybrids. Her experience includes in-vitro culture of hematologic and solid-tumor cell lines, in-vivo murine handling and dosing (oral, intraperitoneal, […]<\/p>\n","protected":false},"author":1,"featured_media":17740,"parent":7534,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"_joinchat":[],"footnotes":""},"class_list":["post-17492","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/immunotherapymx.com\/es\/wp-json\/wp\/v2\/pages\/17492","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/immunotherapymx.com\/es\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/immunotherapymx.com\/es\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/immunotherapymx.com\/es\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/immunotherapymx.com\/es\/wp-json\/wp\/v2\/comments?post=17492"}],"version-history":[{"count":0,"href":"https:\/\/immunotherapymx.com\/es\/wp-json\/wp\/v2\/pages\/17492\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/immunotherapymx.com\/es\/wp-json\/wp\/v2\/pages\/7534"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/immunotherapymx.com\/es\/wp-json\/wp\/v2\/media\/17740"}],"wp:attachment":[{"href":"https:\/\/immunotherapymx.com\/es\/wp-json\/wp\/v2\/media?parent=17492"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}