Stem Cell Therapy for Heart Failure
- Potential improvement in left ventricular ejection fraction (LVEF)
- Reduced fibrosis and inflammation after cardiac injury
- Better exercise tolerance and quality of life
- 4.7-star Google rating
- HIPAA-secure
- Patients from 12 + countries
Is heart failure quietly shrinking your world?
It’s not just numbers on an echo report. It’s getting winded on the stairs, needing extra pillows to sleep, ankles that swell by afternoon, and a kind of tired that doesn’t lift with rest. It’s planning your day around shortness of breath, counting sodium and fluids, juggling medications, and worrying about the next ER visit. Good days feel fragile; bad days feel like your life is getting smaller.
What hurts most is the unpredictability. Family plans get canceled, walks get shorter, and the things that used to feel easy now take effort and recovery time. You want more than another adjustment to your pills—you want a path that helps you do the basics with less fear and more confidence.
Why this happens (in simple terms): Heart failure isn’t only a “weak pump.” After injury or years of pressure and strain, the heart and vessels can stay inflamed and develop stiff, fibrotic tissue. That scarring and inflammation feed the cycle of breathlessness and fatigue, even when you’re doing everything right with standard care.
A Science-Led Approach to Repair, Not Just Relief
Improved Cardiac Function
Research shows that mesenchymal and cardiac-derived stem cells can release growth factors that help damaged heart tissue work more efficiently, potentially improving ejection fraction (LVEF).
Reduced Inflammation and Fibrosis
Stem-cell-derived bio-signals help calm chronic inflammation and may limit the scarring that stiffens heart muscle after injury.
New Microvascular Growth
The therapy promotes angiogenesis — the creation of new capillaries — improving oxygen delivery and nutrient flow in areas previously starved of circulation.
Better Exercise Tolerance and Energy
As cardiac output stabilizes and oxygenation improves, many patients report less fatigue and greater capacity for daily activity.
Quality-of-Life Gains
As cardiac output stabilizes and oxygenation improves, many patients report less fatigue and greater capacity for daily activity.
Objective, Transparent Monitoring
Every case includes baseline and periodic evaluations to compare real metrics, ensuring the plan adapts to your progress safely and ethically.
Successful Stem Cell Therapy for Heart Failure: Clinical Case Study
Condition: Chronic heart failure
Patient: Male, 63 years old
Clinical Background
The patient presented a history of coronary angioplasty, dyslipidemia, infrarenal aortic aneurysm, and depression. He reported shortness of breath on moderate exertion, stable angina, fatigue, cough, orthopnea, and lower limb edema.
His medical record included a prior acute myocardial infarction with the placement of three coronary stents, performed in 2007 and again in October 2021, along with documented dyslipidemia and an infrarenal aortic aneurysm.
Evolution and Imaging Findings
Echocardiographic follow-up revealed slight remodeling and intrinsic dilation of the left ventricle. After undergoing regenerative treatment with mesenchymal stem cells (MSC), the patient showed a notable improvement in cardiac performance.
The left ventricular ejection fraction (LVEF), calculated by the Teichholz method, increased from 41% (March 10, 2022) to 63% (October 10, 2022) — a relative improvement of 22%.
Segmental mobility changes persisted, with mild hypokinesia in the mid-basal septal, apical, and mid-lateral regions; however, no intracavitary thrombi or masses were observed.
Ejection Fraction Comparison
| Date | LVEF |
|---|---|
| 10.03.2022 | 41% |
| 10.10.2022 | 63% |
A Measured, Transparent, and Safe Protocol
Assessment — Understanding Your Cardiac Profile
Before any intervention, we perform a comprehensive medical evaluation to understand your heart’s current condition and recovery potential. This includes reviewing your medical history, imaging, and overall functional status to establish a clear baseline. The evaluation includes specialized cardiac assessment to confirm that the regenerative plan aligns safely with your ongoing medical treatment.
Preconditioning — Preparing the Biological Terrain
Once your baseline is defined, we prepare the internal environment so it can respond optimally to the cellular phase. This step may include plasmapheresis to help remove circulating inflammatory mediators and metabolic residues, along with complementary strategies such as metabolic-nutritional support, safe immune modulation, and methods that enhance microcirculation and redox balance. The goal is to lower the inflammatory and toxic burden, creating a clean, receptive biological terrain — never limited to a single therapy.
Regenerative Session — Mesenchymal Stem Cell Therapy (MSC)
The central phase involves the controlled administration of mesenchymal stem cells (MSC), which act through paracrine signaling — releasing bioactive molecules that promote tissue repair, angiogenesis, and modulation of fibrosis. Exosomes are a core component of the protocol, enhancing intercellular communication. When indicated, the session can be complemented with other advanced cell-based therapies, such as MISID. All biological materials are handled with batch traceability, sterile conditions, and full clinical supervision throughout the procedure.
Aftercare and Clinical Guidance — Clarity Before Every Decision
Following the regenerative phase, patients receive structured guidance and review, contrasting outcomes with baseline data. Decisions to maintain, adjust, or pause the plan are based on objective criteria and transparent communication. You receive clear, easy-to-understand reports that can also be shared with your primary physician. Our focus is straightforward: progress supported by data, clinical prudence, and realistic expectations.
Treatment parameters—dose, frequency, sequence, route and site of administration—and any adjunctive therapies are individualized following a comprehensive clinical evaluation and aligned with your objectives. We do not offer standardized treatment packages.
Why choose immunotherapy Regenerative Medicine?
Expert-guided, lab-developed, patient-centered: our immunotherapy is built around you.
Over 20 Years of Medical Experience
We’ve been pioneers in regenerative and integrative medicine for over two decades—led by a team of physicians, scientists, and clinical specialists.
In-House Advanced Stem Cell Lab
Our on-site lab produces high-viability mesenchymal stem cells (97–99%) under strict quality control—ensuring safety, potency, and consistency.
Comprehensive, Multimodal Therapies
We combine stem cells, exosomes, peptides, ozone, and detox strategies—targeting multiple pathways for maximum therapeutic benefit.
Full-Spectrum Patient Care
From initial assessment to long-term monitoring, we support your healing process every step of the way—with medical, emotional, and logistical care.
Truly Personalized Programs
Every protocol is built around your biology, goals, and medical history—no templates, no shortcuts. Just science-based precision care.
Trusted by Patients Worldwide
We welcome patients from across the globe who are seeking safe, ethical, and advanced cell-based therapies backed by science.
Regulated & Transparent
We follow strict safety standards aligned with COFEPRIS and FDA-equivalent protocols, ensuring medical ethics, transparency, and quality.
Travel-Ready Concierge Support
Our international concierge team offers guidance on ground transportation, lodging options, laboratory coordination, and general assistance throughout your visit.
Our Patients Experience
Posted on Mary GatfieldTrustindex verifies that the original source of the review is Google. I had my procedure on May 14 ....I cannot believe the improvement in my vision more than 50% better. Im able to get a drivers license..I didn't think I would ever drive again. Immunotherapy was there for me from the very beginning,so helpful and supportive. Absolutely the best experience I've ever had dealing with the medical community. I highly recommend having stemcell therapy. I will be going back to Immunotherapy for a booster to get my vision 100%Posted on Rosie VerdugoTrustindex verifies that the original source of the review is Google. Al principio tenía un poco de desconfianza, pero desde el momento en que llegué quedé impresionado. El lugar es hermoso, muy limpio y con un ambiente profesional y tranquilo. Todo el personal fue sumamente amable, atento y respetuoso. Los doctores me brindaron un servicio excelente y se tomaron el tiempo para explicarme todo con claridad. Me sentí muy bien atendido y cuidado en todo momento. Sin duda recomiendo este consultorio a cualquier persona que esté considerando un tratamiento con células madre. ¡Una experiencia maravillosa! 🙏💫 Y si te piden un depósito para hacer tu cita no te preocupes son muy honestos !! Cuando gustes llamar te recomiendo preguntes por Chantal ella es una excelente recepcionista!!Posted on Denny CorbettTrustindex verifies that the original source of the review is Google. Staff members were very professional, polite, and experienced. Everyone took the time to explain and answer any and all questions. The procedures went well with no issues. It was a comfortable experience.Posted on Ryan DobleTrustindex verifies that the original source of the review is Google. I attended their clinic in Puerto Vallarta from the UK for my vaccine damage/long covid and Crohn’s. The whole process from initial contact with their team, assessing my current health and issues, creating an individual plan of treatment and then receiving the treatment far exceeded my expectations. The whole team including the point of contact, doctors and all of the nurses were very professional, caring and made sure I was at ease and completely comfortable through the whole treatment. It is too early for me to gauge the final success of my treatment but due to being unknown and complicated it will take some time for the stem cells and other treatments to do their work which is expected. However from everything I have tried previously, this is the only thing I have done which I have already noticed some small improvements, which is hopefully a start of my full healing. Thanks to the teamPosted on RMTrustindex verifies that the original source of the review is Google. I did extensive research to find the right stem cell clinic - thoroughly looking all over the world. I came upon this clinic, who was also highly recommended by another friend who had gone there. She explained everything to me, and I decided to give them a call - lo and behold I talked to Cesar Romero and from that point forward he has been the patient coordinator for the last 5 patients that I have sent to the clinic. They first do an personalized consultation to draw up a program after you send them any and all medical information on your situation. Then they do a consultation with a Doctor who goes over what the treatments they do and what they offer. Following this and the discussion of your goals, they make a tailored program. Every step of the way all of the staff members and medical professionals are extremely caring. They deliver this out of an upstat building in puerto vallarta. They are medically competent in all aspects of what they do, and they explain everything. Cesar is the best - but all of the staff deserve and huge thank you for all they do. It is clear that they are doing it literally to help people - which is rare these days. It was late on Friday when I told Cesar that my next 2 friends would be coming, and even though it was late he went and drove to the lab to make sure that there would be stem cells available for when they had to start. You do need to heal after stem cells, and it can take some time to show up and give you all the results you need. You cannot expect instant results. But they do come, and it is worth it. Thank you to the entire Immune Regenerative Clinic - what you are doing is ground breaking and so important. I appreciate all that you have done for Julie, Roberta, Adrienne, Dave and Andres.Posted on Brendan Evans MooreheadTrustindex verifies that the original source of the review is Google. I'm glad that I chose your clinic to receive the plasmapheresis that I was seeking. Thank you nurse Aaron, Dr. Rosas, and Dr. Padilla for your attentive care. I look forward to returning to receive more services some time in the future.Posted on A YtTrustindex verifies that the original source of the review is Google. El Dr. Javier Arenas me explico detalladamente sobre las celulas madre, se tomo el tiempo de escuchar mi problema, muy profesional 100% recomendable, agradecer igualmente a Dinora Alvarez la coordinadora por haber hecho posible la comunicacion con el Dr. excelente servicio.Posted on OmarTrustindex verifies that the original source of the review is Google. I went here last week, had a wonderful experience everyone is super nice and speaks english. The doctor is very knowledgeable and does everything they can to help your situation. The facilities are extremely clean and comfortable. Every nurse I had an interaction with helped me feel comfortable and at home. I had IV, Facial, and Intrathecal. Was worried about potential side effects but suffered no negative effects. I have 0 complaints or regrets, I hope to return someday. Truly a world class experience, highly recommended.Verified by TrustindexTrustindex verified badge is the Universal Symbol of Trust. Only the greatest companies can get the verified badge who has a review score above 4.5, based on customer reviews over the past 12 months. Read more
FAQs: Stem Cell Therapy for Heart Failure in Mexico
Where do the stem cells used in this therapy come from, and how is their safety guaranteed?
All biological materials used in our program come from licensed and COFEPRIS-authorized laboratories in Mexico. Each product undergoes microbiological, sterility, and viability testing before clinical use, and complete batch traceability is maintained from origin to administration. These strict regulatory controls ensure patient safety and the consistency of every treatment.
How is the cost of treatment determined, and what does it include?
Treatment cost is individualized based on your clinical profile, stage of heart failure, and the combination of therapies indicated (e.g., plasmapheresis, MSC + exosome session, supportive care). Every program includes medical assessment, personalized planning, and all necessary procedures during the clinical phase.
Pricing typically ranges from USD $10,000 to $40,000, depending on complexity and duration. Before any commitment, patients receive a transparent written quote detailing what’s included — no hidden fees or generalized pricing.
When might I notice changes, and how are results evaluated?
Heart failure recovery is progressive and depends on baseline damage, concurrent medical management, and adherence to the plan. Some patients report improvements in stamina and breathing within weeks, while structural changes may take longer. We use objective comparisons to your baseline, such as clinical markers and functional capacity, to track real progress over time.
How do I know if I’m a good candidate for stem cell therapy for heart failure?
Candidacy is determined through comprehensive medical and cardiac evaluation. We assess the cause and severity of heart failure, organ function, medications, and recent cardiovascular events. This therapy is designed to complement, not replace, standard medical care. The objective is to identify cases where regenerative therapy may provide measurable benefit safely and responsibly.
What are the potential risks or side effects, and how are they managed?
Stem cell therapy is generally well tolerated when performed under sterile, regulated conditions. Mild fatigue or transient inflammation at the infusion site may occur. Serious complications are rare, and safety is reinforced through COFEPRIS-regulated protocols, aseptic technique, and medical supervision throughout the procedure. Each patient is monitored carefully before, during, and after therapy.
How long does the process take, and what type of follow-up do you offer?
The complete process — from initial assessment to post-therapy guidance — usually spans a few weeks, depending on preparation and response. After the regenerative phase, patients receive structured guidance and coordination to ensure continuity of care. Our medical team remains available for follow-up discussions, ensuring transparency and informed decision-making at every stage.