Stem Cell Therapy for Shoulder Pain & Rotator Cuff Tears
- Regenerative medicine specialists experienced in shoulder and joint care
- Onsite certified lab ensuring cell viability and authenticity (98–99%)
- Personalized treatment protocols with realistic timelines and follow-up care
- 4.7-star Google rating
- HIPAA-secure
- Patients from 12 + countries
Why Does Your Shoulder Pain Keep Coming Back — Even After Everything You’ve Tried?
It probably started as a small discomfort — a “pinch” after a workout, lifting weight, or playing your favorite sport. You assumed it would heal with rest or physical therapy, but the pain never really went away. Now it keeps you from sleeping on that side, limits how high you can raise your arm, and has forced you to give up golf, tennis, or the gym you once enjoyed. You’ve done the right things, yet the pain returns. Steroid injections only bring temporary relief, and surgery feels like a last resort — months of painful recovery with no guarantee of getting back to normal.
The reason these treatments fail is that they don’t address the biological root of the problem. A rotator cuff tear or shoulder arthritis isn’t just a “mechanical” issue — it’s a cellular crisis. Damaged tissue becomes trapped in a cycle of chronic inflammation and degeneration, overwhelming your body’s natural ability to repair itself. Conventional treatments only mask pain, while regenerative medicine aims to restore balance by reactivating the body’s own repair signals — the paracrine factors that support true, functional healing of tendon and cartilage tissue.
Real Results: Restoring Function — Not Just Masking Pain
Sustained Pain Reduction
Addresses inflammation at the cellular level, offering deeper and longer-lasting relief than conventional steroid-based treatments.
Recovery of Shoulder Mobility
Focuses on restoring shoulder range of motion, reducing stiffness, and improving daily activities such as lifting your arm or sleeping comfortably.
Superior Cell Potency (98–99% Viability)
Uses fresh, never frozen MSCs, maintaining 98–99% cell viability to preserve biological potency and maximize anti-inflammatory signaling capacity.
Specialist-Guided Protocols
Every treatment is supervised by regenerative medicine specialists, ensuring expert oversight and individualized care rather than a one-size-fits-all protocol.
A Powerful Alternative to Surgery
Every treatment is supervised by regenerative medicine specialists, ensuring expert oversight and individualized care rather than a one-size-fits-all protocol.
Synergy with Physical Therapy
By reducing baseline pain and inflammation, this approach enhances the effectiveness of physiotherapy, accelerating the return of strength and shoulder stability.
Our Medical Protocol: Transparency and Safety in Four Steps
Step 1: Comprehensive Evaluation and Medical Diagnosis
Your journey starts with a detailed review of your case by our clinical team. We analyze your existing imaging studies (X-rays, MRIs) and medical history to identify the true source of your shoulder pain. Eligibility is based on strict medical criteria — we only treat patients who can genuinely benefit from a regenerative approach.
Step 2: Laboratory Preparation and Quality Control (Our Key Differentiator)
This is where our critical advantage lies. Unlike procedures using frozen or office-processed material, our therapy employs fresh mesenchymal stem cells (MSCs) handled in our COFEPRIS-certified onsite laboratory.
Each batch is cultured, tested, and validated to ensure 98–99% cell viability, maintaining the highest biological potency and authenticity. This level of control guarantees that you receive one of the most reliable and consistent regenerative products available.
Step 3: Clinical Administration of the Therapy
Your treatment is performed in a sterile clinical environment by our medical specialists. The application is minimally invasive and precisely targeted to the affected areas of the shoulder. The high-viability MSCs act to modulate chronic inflammation and deliver potent biological signals (paracrine factors) that support functional recovery and tissue repair over time.
Step 4: Follow-Up and Functional Recovery Plan
Our commitment continues long after your visit. Every patient receives a structured follow-up plan, including rehabilitation guidance and progress monitoring. We maintain open communication to track your functional improvement and ensure you have medical support throughout your recovery process.
Treatment parameters—dose, frequency, sequence, route and site of administration—and any adjunctive therapies are individualized following a comprehensive clinical evaluation and aligned with your objectives. We do not offer standardized treatment packages.
Why choose immunotherapy Regenerative Medicine?
Expert-guided, lab-developed, patient-centered: our immunotherapy is built around you.
Over 20 Years of Medical Experience
We’ve been pioneers in regenerative and integrative medicine for over two decades—led by a team of physicians, scientists, and clinical specialists.
In-House Advanced Stem Cell Lab
Our on-site lab produces high-viability mesenchymal stem cells (97–99%) under strict quality control—ensuring safety, potency, and consistency.
Comprehensive, Multimodal Therapies
We combine stem cells, exosomes, peptides, ozone, and detox strategies—targeting multiple pathways for maximum therapeutic benefit.
Full-Spectrum Patient Care
From initial assessment to long-term monitoring, we support your healing process every step of the way—with medical, emotional, and logistical care.
Truly Personalized Programs
Every protocol is built around your biology, goals, and medical history—no templates, no shortcuts. Just science-based precision care.
Trusted by Patients Worldwide
We welcome patients from across the globe who are seeking safe, ethical, and advanced cell-based therapies backed by science.
Regulated & Transparent
We follow strict safety standards aligned with COFEPRIS and FDA-equivalent protocols, ensuring medical ethics, transparency, and quality.
Travel-Ready Concierge Support
Our international concierge team offers guidance on ground transportation, lodging options, laboratory coordination, and general assistance throughout your visit.
Posted on Denny CorbettTrustindex verifies that the original source of the review is Google. Staff members were very professional, polite, and experienced. Everyone took the time to explain and answer any and all questions. The procedures went well with no issues. It was a comfortable experience.Posted on Ryan DobleTrustindex verifies that the original source of the review is Google. I attended their clinic in Puerto Vallarta from the UK for my vaccine damage/long covid and Crohn’s. The whole process from initial contact with their team, assessing my current health and issues, creating an individual plan of treatment and then receiving the treatment far exceeded my expectations. The whole team including the point of contact, doctors and all of the nurses were very professional, caring and made sure I was at ease and completely comfortable through the whole treatment. It is too early for me to gauge the final success of my treatment but due to being unknown and complicated it will take some time for the stem cells and other treatments to do their work which is expected. However from everything I have tried previously, this is the only thing I have done which I have already noticed some small improvements, which is hopefully a start of my full healing. Thanks to the teamPosted on RMTrustindex verifies that the original source of the review is Google. I did extensive research to find the right stem cell clinic - thoroughly looking all over the world. I came upon this clinic, who was also highly recommended by another friend who had gone there. She explained everything to me, and I decided to give them a call - lo and behold I talked to Cesar Romero and from that point forward he has been the patient coordinator for the last 5 patients that I have sent to the clinic. They first do an personalized consultation to draw up a program after you send them any and all medical information on your situation. Then they do a consultation with a Doctor who goes over what the treatments they do and what they offer. Following this and the discussion of your goals, they make a tailored program. Every step of the way all of the staff members and medical professionals are extremely caring. They deliver this out of an upstat building in puerto vallarta. They are medically competent in all aspects of what they do, and they explain everything. Cesar is the best - but all of the staff deserve and huge thank you for all they do. It is clear that they are doing it literally to help people - which is rare these days. It was late on Friday when I told Cesar that my next 2 friends would be coming, and even though it was late he went and drove to the lab to make sure that there would be stem cells available for when they had to start. You do need to heal after stem cells, and it can take some time to show up and give you all the results you need. You cannot expect instant results. But they do come, and it is worth it. Thank you to the entire Immune Regenerative Clinic - what you are doing is ground breaking and so important. I appreciate all that you have done for Julie, Roberta, Adrienne, Dave and Andres.Posted on Brendan Evans MooreheadTrustindex verifies that the original source of the review is Google. I'm glad that I chose your clinic to receive the plasmapheresis that I was seeking. Thank you nurse Aaron, Dr. Rosas, and Dr. Padilla for your attentive care. I look forward to returning to receive more services some time in the future.Posted on A YtTrustindex verifies that the original source of the review is Google. El Dr. Javier Arenas me explico detalladamente sobre las celulas madre, se tomo el tiempo de escuchar mi problema, muy profesional 100% recomendable, agradecer igualmente a Dinora Alvarez la coordinadora por haber hecho posible la comunicacion con el Dr. excelente servicio.Posted on OmarTrustindex verifies that the original source of the review is Google. I went here last week, had a wonderful experience everyone is super nice and speaks english. The doctor is very knowledgeable and does everything they can to help your situation. The facilities are extremely clean and comfortable. Every nurse I had an interaction with helped me feel comfortable and at home. I had IV, Facial, and Intrathecal. Was worried about potential side effects but suffered no negative effects. I have 0 complaints or regrets, I hope to return someday. Truly a world class experience, highly recommended.Posted on Arminda MotaTrustindex verifies that the original source of the review is Google. I was dismissed and misdiagnosed by conventional medicine for years until I found this clinic. From my first virtual consultation with Dr. Alejandra Rojas, I knew I was in the right place. She listened with care, explained everything clearly, and created a protocol tailored to my condition. Throughout treatment, she remained fully present, always responsive, precise, and supportive. Her depth of knowledge, empathy, and commitment makes her truly exceptional. The medical team, Dr. Luis Padilla, Dr. Jose Rosas, and Dr. Karla Castolo, were equally professional, kind, and focused. Their collaborative approach gave me confidence and stability at every stage. I felt safe and closely monitored the entire time. The nursing staff was outstanding. Torres and Miriam were my main nurses. Their skill and kindness made a real difference daily. Andrea and Pamela also cared for me with professionalism and warmth. Sarah, at reception, went far beyond her role. In the heat of the day, she picked up lunch for me every day just to help. She even made me a handmade necklace that deeply touched me. And on my birthday, the team surprised me with a cake. Every gesture, large or small, meant something and none of it went unnoticed. Abel, the patient coordinator, deserves special thanks. From the very first contact, his warmth and efficiency set the tone. He guided me through every detail, stayed in constant contact, and helped far beyond expectation. His presence made a lasting difference. We became true friends through the process, and I will always be grateful for his support. Lorena Shira, the clinic director, personally explained their lab protocols, ethics, and research collaboration. I was impressed by the transparency and integrity throughout. Their mesenchymal stem cells are ethically sourced and never frozen, produced in-house at their Puerto Vallarta lab under strict protocols. They operate independently and collaborate with UNAM in a national regenerative medicine initiative. I am now continuing my protocol at home with their support and follow-up. They remain fully engaged in my care, and I am hopeful for the results. This clinic is not just a medical provider. It is a place of real care, professionalism, and humanity. I received more than treatment. I will always be grateful.Posted on MARYTERESE WALLACETrustindex verifies that the original source of the review is Google. Thanks so much! Your group seem very organized. Called promptly at the scheduled time. Looking forward to the email with more info.Verified by TrustindexTrustindex verified badge is the Universal Symbol of Trust. Only the greatest companies can get the verified badge who has a review score above 4.5, based on customer reviews over the past 12 months. Read more
Frequently Asked Questions About Stem Cell Therapy for Shoulder Pain
What type of stem cells are used for shoulder pain, and how do you ensure their quality?
We use only mesenchymal stem cells (MSCs) — known for their strong anti-inflammatory and immunomodulatory properties.
Our key differentiator is quality control. All cells are prepared in our COFEPRIS-certified onsite laboratory, never frozen or stored long-term. Each batch is tested and verified for 98–99% viability, ensuring a potent, biologically active product rather than a low-quality or unverified sample.
How much does stem cell therapy for shoulder pain cost in Mexico, and what does it include?
The cost of stem cell therapy for shoulder pain in Mexico varies depending on your diagnosis and the complexity of your case.
Treatment costs typically range between $1,900 and $5,000 USD, depending on the severity of the injury and the protocol recommended. We provide detailed, personalized cost estimates after your free medical evaluation.
While these treatments are not usually covered by insurance, patients often find that prices in Mexico are significantly lower than in the U.S. or Canada.
Your investment includes the specialist medical assessment, the high-viability (98–99%) cell product, clinical administration, and follow-up guidance — representing a high-value alternative to shoulder replacement surgery, with less downtime, less pain, and faster recovery.
Will stem cell therapy regenerate my rotator cuff? When will I see results?
It’s important to be scientifically honest: claims of full “tendon regeneration” are often exaggerated. Current evidence shows mixed results regarding structural regeneration on MRI.
The realistic and measurable goal is functional recovery. MSCs act as signaling cells that calm chronic inflammation and send repair signals (paracrine factors) to damaged tissue. Most patients report improvements in pain (VAS) and shoulder function (WOMAC or range-of-motion testing) within 3 to 6 months after treatment.
Am I a candidate for this therapy? Is it better than shoulder surgery?
The ideal candidate is someone with chronic shoulder pain caused by arthritis or partial rotator cuff tears who wants a non-surgical alternative.
Eligibility is determined through a thorough review of your MRI and medical history by our specialists. This is not a “miracle cure,” but a biological, evidence-based option many patients choose to avoid the invasiveness, extended recovery, and risks associated with major surgery.
What are the risks or side effects of stem cell shoulder injections?
Safety is our highest priority — especially for international patients.
Short-term effects: mild pain, swelling, or temporary fluid accumulation at the injection site, usually resolving within 48–72 hours.
Long-term risks: theoretical concerns such as tumor formation or immune reactions have not been observed in human clinical trials using MSCs.
Our sterile clinical environment and COFEPRIS-certified laboratory minimize infection risk and guarantee a pure, uncontaminated cellular product.
How does the process work for patients traveling from the U.S. or Canada?
Our program is designed specifically for medical travelers:
Step 1 – Remote Evaluation: Schedule a free online consultation and share your medical records and MRI. Our team reviews them to confirm candidacy before you travel.
Step 2 – Treatment in Mexico: The therapy is a minimally invasive outpatient procedure performed at our clinic in Puerto Vallarta.
Step 3 – Follow-Up: After you return home, our medical team provides structured remote follow-ups to track your progress and support your recovery.