Non-Surgical Stem Cell Therapy for Shoulder Pain & Rotator Cuff Injuries
Struggling with shoulder pain, limited mobility, or a torn rotator cuff? Discover a regenerative, minimally invasive alternative designed to repair tissue, reduce inflammation, and help you regain full range of motion — without surgery.
- Targets shoulder arthritis, labral tears, and rotator cuff injuries
- Image-guided injections with mesenchymal stem cells and PRP
- Faster recovery with no hospital stay required
Understanding Shoulder Pain & Rotator Cuff Injuries
The shoulder is one of the most mobile and complex joints in the human body — and also one of the most vulnerable to injury. Whether caused by wear and tear, trauma, or overuse, conditions such as rotator cuff tears, labral injuries, tendonitis, and shoulder arthritis can severely impact mobility and quality of life.
When the soft tissues surrounding the shoulder joint become damaged or inflamed, patients often experience:
Persistent pain (especially when lifting or sleeping on the side)
Limited range of motion
Weakness in the arm and shoulder
Clicking or catching sensations
Difficulty performing everyday tasks
Traditional treatments like corticosteroid injections or surgery may provide temporary relief, but they often fail to repair the underlying damage — and in many cases, involve long recovery times.
How Stem Cell Therapy Helps Restore Shoulder Function
Stem cell therapy offers a minimally invasive, regenerative alternative to shoulder surgery — especially for individuals with rotator cuff tears, labral injuries, or arthritis-related degeneration.
Our protocol uses mesenchymal stem cells (MSCs), known for their ability to:
Reduce inflammation
MSCs modulate the immune response to calm chronic inflammation, a key cause of shoulder joint deterioration.
Promote tissue regeneration
They stimulate the repair of damaged tendons, cartilage, and joint structures — helping restore strength and mobility.
Support collagen synthesis
Essential for repairing rotator cuff and labral tissues, especially in partial or moderate tears.
Improve circulation and healing environment
When combined with PRP (Platelet-Rich Plasma), the therapy boosts the regenerative potential and speeds recovery.
Step-by-Step: Your Personalized Stem Cell Shoulder Treatment
Our protocol is designed to treat not just symptoms — but the root cause of shoulder pain and dysfunction. Here’s what your personalized regenerative journey looks like:
1. Initial Consultation & Medical Evaluation
We start with an in-depth clinical and imaging assessment. Our medical team evaluates the condition of your shoulder (rotator cuff, labrum, joint cartilage, etc.) to determine if you’re a good candidate.
2. Personalized Regenerative Protocol
Once approved, we design a treatment plan tailored to your condition, age, activity level, and medical history.
Our protocol may include:
Mesenchymal Stem Cells (MSCs) cultured in our in-house lab
Platelet-Rich Plasma (PRP) to enhance regenerative signaling
Ozone therapy to improve oxygenation and anti-inflammatory response
IV peptide therapy and micronutrient support for systemic rejuvenation
3. Precise Stem Cell Injection Under Imaging Guidance
The MSCs are injected directly into the damaged shoulder structures using real-time imaging (ultrasound or fluoroscopy). This ensures high accuracy and maximizes therapeutic potential.
The procedure is minimally invasive, performed in a sterile environment, and typically takes less than 90 minutes.
4. Recovery and Follow-Up Support
There is no hospitalization or general anesthesia required. Most patients resume daily activities within 3 to 7 days.
Our team monitors your progress and adjusts your recovery plan as needed.
Follow-ups may include mobility assessments, nutritional guidance, and optional supportive therapies like PRP boosters or additional IV sessions.

Why Does Shoulder Pain Occur?
The shoulder is one of the most versatile joints in the body, making it prone to wear and tear over time. Conditions such as arthritis, rotator cuff injuries, and ligament tears can lead to chronic pain and limited mobility.
Common Causes of Shoulder Pain
- Shoulder Arthritis: Degenerative joint disease causes cartilage breakdown, leading to pain and stiffness.
- Rotator Cuff Injuries: Tears or inflammation in the tendons affect the joint’s stability and function.
- Labral Tears: Damage to the cartilage ring supporting the shoulder joint results in discomfort and instability.
Traditional treatments like physical therapy or surgery often fall short in addressing the root cause of the problem. This is where stem cell injections for shoulders come in, offering a regenerative approach to healing.
Why Patients Choose Our Stem Cell Shoulder Program
At Immunotherapy Regenerative Medicine, we don’t just treat shoulder pain — we treat people.
Our approach blends scientific rigor, personalized care, and over 20 years of clinical experience to deliver results that matter.
Discover what sets us apart through these key advantages:
Over 20 Years of Medical Experience
We’ve been pioneers in regenerative and integrative medicine for over two decades—led by a team of physicians, scientists, and clinical specialists.
In-House Advanced Stem Cell Lab
Our on-site lab produces high-viability mesenchymal stem cells (97–99%) under strict quality control—ensuring safety, potency, and consistency.
Comprehensive, Multimodal Therapies
We combine stem cells, exosomes, peptides, ozone, and detox strategies—targeting multiple pathways for maximum therapeutic benefit.
Full-Spectrum Patient Care
From initial assessment to long-term monitoring, we support your healing process every step of the way—with medical, emotional, and logistical care.
Truly Personalized Programs
Every protocol is built around your biology, goals, and medical history—no templates, no shortcuts. Just science-based precision care.
Trusted by Patients Worldwide
We welcome patients from across the globe who are seeking safe, ethical, and advanced cell-based therapies backed by science.
Regulated & Transparent
We follow strict safety standards aligned with COFEPRIS and FDA-equivalent protocols, ensuring medical ethics, transparency, and quality.
Travel-Ready Concierge Support
Our international concierge team offers guidance on ground transportation, lodging options, laboratory coordination, and general assistance throughout your visit.
Our Patients Experience
Cornelia Liebmann2025-05-08Trustindex verifies that the original source of the review is Google. I am very afraid of needles to a point that I pass out when someone takes my blood so naturally I was really afraid of the procedure. From the beginning of my healing journey I felt I was in the very best hands. Mariana was always by my side and explained everything to me before and after the treatment. The nurse who took my blood laid me flat in a comfortable chair and I did not even feel anything while she took my blood. The same with the procedure itself I did not feel a thing and it was over before I knew it. Thanks to the whole team and especially Mariana for this amazing journey. I can not thank them enough and I am very grateful and excited for what is to come. Jim Affleck2025-05-05Trustindex verifies that the original source of the review is Google. I came to Immunotherapy Regenerative Medicine April 24/25 for stem cell injections in both knee's. the experience was professional and positive, from the first contact to the completion everyone I had contact with was extremely helpful. Cesar Romero my Patient Coordinator was there for me every step of the way, answering questions and arranging contact with the Dr. All of the nurses and staff at the clinic were professional and helpful. The Dr. explained all the procedures before and answered all of my questions. Dr. Luis Francisco Padilla also explained the entire procedure and what to do after treatment, he did a fantastic job. Thank You, I would recommend this clinic to anyone. Edvin Bresha2025-04-24Trustindex verifies that the original source of the review is Google. Very professional clinic . They took things very seriously checking bloodwork, electrocardiogram of the heart and ultrasound of the heart also . Asking in details about the medical history and also professional nursing stuff make the clinic very good . Clinic is very well located in the very center of the city make it easy to access. Very friendly stuff Gunars Gunars2025-04-23Trustindex verifies that the original source of the review is Google. Was good explanation about treatment and doctor was poly and helphul. Bruni Hagen2025-04-08Trustindex verifies that the original source of the review is Google. Everything was more than we had expected, very friendly staff, clean facility, you felt that they care for your well being Ryan Gonzales2025-04-07Trustindex verifies that the original source of the review is Google. Ceaser and his team are amazing! I did my first Ozone therapy with them and I am hooked. I healed from a Sunburn in only 1 day shortly after my treatment and my skin didn’t even peel. My energy levels are increased and I feel that the treatment is well worth it. Looking forward to trying other services in the feature. Mike Christopher2025-04-05Trustindex verifies that the original source of the review is Google. Last week I had the pleasure of attending the Immunotherapy Regenerative Medicine clinic in Puerto Vallarta, Mexico, for stem cell therapy. I went through an extensive vetting process prior to choosing their clinic and after spending 5 days with them I felt I had definitely picked the right facility. Their well-located clinic is very modern, comfortable, and clean. They have a young, dynamic and professional staff of doctors, nurses, techs and support staff that were very accommodating, never rushed and clearly explained all the various treatments administered and answered all my questions. In addition, they maintain their own lab in which the stem cells are thoroughly processed, which removed any concern over the quality and source. Totally different than the typical USA medical experience. I can highly recommend them to anyone considering stem cell therapy. I am looking forward to experiencing the benefits of the protocols provided. Mike from CA Joseph Kleinsasser2025-03-14Trustindex verifies that the original source of the review is Google. There is so much to share but I will make it short an sweet .The hospitality at Immunotherapy Regenerative Medicine is out standing If asked I would advice anybody to go there. And again will thank the whole team at Immunotherapy . Best regards Joseph Kleinsasser Jessica Kleinsasser and Rial PATEVerified by TrustindexTrustindex verified badge is the Universal Symbol of Trust. Only the greatest companies can get the verified badge who has a review score above 4.5, based on customer reviews over the past 12 months. Read more
Frequently Asked Questions About Stem Cell Therapy for Shoulder Pain
Is stem cell therapy safe for shoulder conditions like rotator cuff tears or arthritis?
Yes. We use mesenchymal stem cells processed under strict clinical-grade conditions, following safety protocols aligned with international standards. No cryopreservation is involved—only fresh, high-viability cells are used.
How soon will I notice improvement after the procedure?
Many patients begin to notice reduced inflammation and increased mobility within a few weeks. However, regenerative processes continue developing over the following 3 to 6 months, with full benefits becoming evident over time.
Can stem cells help me avoid rotator cuff surgery?
In many cases, yes. Stem cell therapy may serve as a non-surgical alternative by promoting tissue repair, reducing pain, and improving function—especially in partial tears or early degeneration. For full-thickness tears, candidacy is determined case by case.
What’s the difference between this therapy and corticosteroid injections?
While corticosteroids temporarily suppress inflammation, stem cell therapy targets the root cause by promoting cellular repair and tissue regeneration, offering long-term improvement instead of symptom masking.
Do you combine stem cells with other regenerative therapies?
Yes. Our protocol often includes PRP (Platelet-Rich Plasma), ozone therapy, peptides, or plasmapheresis, depending on your clinical profile. These support healing, reduce oxidative stress, and enhance the effectiveness of the stem cells.
How is the procedure performed? Is it painful?
The injection is performed under image guidance (such as ultrasound or fluoroscopy) for precision. It’s a minimally invasive, outpatient procedure. Some patients report mild post-injection soreness, which typically resolves in a few days.
What’s the recovery time?
Most patients resume light activities within 2 to 5 days. Full physical therapy or athletic return-to-play timelines may vary depending on your condition and treatment plan.
How much does the treatment cost?
Treatment costs typically range between $1,900 and $5,000 USD, depending on the severity of the injury and the protocol recommended. We provide detailed, personalized cost estimates after your free medical evaluation.