Non-Surgical Stem Cell Therapy for Shoulder Pain & Rotator Cuff Injuries
Struggling with shoulder pain, limited mobility, or a torn rotator cuff? Discover a regenerative, minimally invasive alternative designed to repair tissue, reduce inflammation, and help you regain full range of motion — without surgery.
- Targets shoulder arthritis, labral tears, and rotator cuff injuries
- Image-guided injections with mesenchymal stem cells and PRP
- Faster recovery with no hospital stay required
Understanding Shoulder Pain & Rotator Cuff Injuries
The shoulder is one of the most mobile and complex joints in the human body — and also one of the most vulnerable to injury. Whether caused by wear and tear, trauma, or overuse, conditions such as rotator cuff tears, labral injuries, tendonitis, and shoulder arthritis can severely impact mobility and quality of life.
When the soft tissues surrounding the shoulder joint become damaged or inflamed, patients often experience:
Persistent pain (especially when lifting or sleeping on the side)
Limited range of motion
Weakness in the arm and shoulder
Clicking or catching sensations
Difficulty performing everyday tasks
Traditional treatments like corticosteroid injections or surgery may provide temporary relief, but they often fail to repair the underlying damage — and in many cases, involve long recovery times.
How Stem Cell Therapy Helps Restore Shoulder Function
Stem cell therapy offers a minimally invasive, regenerative alternative to shoulder surgery — especially for individuals with rotator cuff tears, labral injuries, or arthritis-related degeneration.
Our protocol uses mesenchymal stem cells (MSCs), known for their ability to:
Reduce inflammation
MSCs modulate the immune response to calm chronic inflammation, a key cause of shoulder joint deterioration.
Promote tissue regeneration
They stimulate the repair of damaged tendons, cartilage, and joint structures — helping restore strength and mobility.
Support collagen synthesis
Essential for repairing rotator cuff and labral tissues, especially in partial or moderate tears.
Improve circulation and healing environment
When combined with PRP (Platelet-Rich Plasma), the therapy boosts the regenerative potential and speeds recovery.
Step-by-Step: Your Personalized Stem Cell Shoulder Treatment
Our protocol is designed to treat not just symptoms — but the root cause of shoulder pain and dysfunction. Here’s what your personalized regenerative journey looks like:
1. Initial Consultation & Medical Evaluation
We start with an in-depth clinical and imaging assessment. Our medical team evaluates the condition of your shoulder (rotator cuff, labrum, joint cartilage, etc.) to determine if you’re a good candidate.
2. Personalized Regenerative Protocol
Once approved, we design a treatment plan tailored to your condition, age, activity level, and medical history.
Our protocol may include:
Mesenchymal Stem Cells (MSCs) cultured in our in-house lab
Platelet-Rich Plasma (PRP) to enhance regenerative signaling
Ozone therapy to improve oxygenation and anti-inflammatory response
IV peptide therapy and micronutrient support for systemic rejuvenation
3. Precise Stem Cell Injection Under Imaging Guidance
The MSCs are injected directly into the damaged shoulder structures using real-time imaging (ultrasound or fluoroscopy). This ensures high accuracy and maximizes therapeutic potential.
The procedure is minimally invasive, performed in a sterile environment, and typically takes less than 90 minutes.
4. Recovery and Follow-Up Support
There is no hospitalization or general anesthesia required. Most patients resume daily activities within 3 to 7 days.
Our team monitors your progress and adjusts your recovery plan as needed.
Follow-ups may include mobility assessments, nutritional guidance, and optional supportive therapies like PRP boosters or additional IV sessions.

Why Does Shoulder Pain Occur?
The shoulder is one of the most versatile joints in the body, making it prone to wear and tear over time. Conditions such as arthritis, rotator cuff injuries, and ligament tears can lead to chronic pain and limited mobility.
Common Causes of Shoulder Pain
- Shoulder Arthritis: Degenerative joint disease causes cartilage breakdown, leading to pain and stiffness.
- Rotator Cuff Injuries: Tears or inflammation in the tendons affect the joint’s stability and function.
- Labral Tears: Damage to the cartilage ring supporting the shoulder joint results in discomfort and instability.
Traditional treatments like physical therapy or surgery often fall short in addressing the root cause of the problem. This is where stem cell injections for shoulders come in, offering a regenerative approach to healing.
Why Patients Choose Our Stem Cell Shoulder Program
At Immunotherapy Regenerative Medicine, we don’t just treat shoulder pain — we treat people.
Our approach blends scientific rigor, personalized care, and over 20 years of clinical experience to deliver results that matter.
Discover what sets us apart through these key advantages:
Why choose immunotherapy Regenerative Medicine?
Expert-guided, lab-developed, patient-centered: our immunotherapy is built around you.
Over 20 Years of Medical Experience
We’ve been pioneers in regenerative and integrative medicine for over two decades—led by a team of physicians, scientists, and clinical specialists.
In-House Advanced Stem Cell Lab
Our on-site lab produces high-viability mesenchymal stem cells (97–99%) under strict quality control—ensuring safety, potency, and consistency.
Comprehensive, Multimodal Therapies
We combine stem cells, exosomes, peptides, ozone, and detox strategies—targeting multiple pathways for maximum therapeutic benefit.
Full-Spectrum Patient Care
From initial assessment to long-term monitoring, we support your healing process every step of the way—with medical, emotional, and logistical care.
Truly Personalized Programs
Every protocol is built around your biology, goals, and medical history—no templates, no shortcuts. Just science-based precision care.
Trusted by Patients Worldwide
We welcome patients from across the globe who are seeking safe, ethical, and advanced cell-based therapies backed by science.
Regulated & Transparent
We follow strict safety standards aligned with COFEPRIS and FDA-equivalent protocols, ensuring medical ethics, transparency, and quality.
Travel-Ready Concierge Support
Our international concierge team offers guidance on ground transportation, lodging options, laboratory coordination, and general assistance throughout your visit.
Our Patients Experience
Posted on Ryan DobleTrustindex verifies that the original source of the review is Google. I attended their clinic in Puerto Vallarta from the UK for my vaccine damage/long covid and Crohn’s. The whole process from initial contact with their team, assessing my current health and issues, creating an individual plan of treatment and then receiving the treatment far exceeded my expectations. The whole team including the point of contact, doctors and all of the nurses were very professional, caring and made sure I was at ease and completely comfortable through the whole treatment. It is too early for me to gauge the final success of my treatment but due to being unknown and complicated it will take some time for the stem cells and other treatments to do their work which is expected. However from everything I have tried previously, this is the only thing I have done which I have already noticed some small improvements, which is hopefully a start of my full healing. Thanks to the teamPosted on RMTrustindex verifies that the original source of the review is Google. I did extensive research to find the right stem cell clinic - thoroughly looking all over the world. I came upon this clinic, who was also highly recommended by another friend who had gone there. She explained everything to me, and I decided to give them a call - lo and behold I talked to Cesar Romero and from that point forward he has been the patient coordinator for the last 5 patients that I have sent to the clinic. They first do an personalized consultation to draw up a program after you send them any and all medical information on your situation. Then they do a consultation with a Doctor who goes over what the treatments they do and what they offer. Following this and the discussion of your goals, they make a tailored program. Every step of the way all of the staff members and medical professionals are extremely caring. They deliver this out of an upstat building in puerto vallarta. They are medically competent in all aspects of what they do, and they explain everything. Cesar is the best - but all of the staff deserve and huge thank you for all they do. It is clear that they are doing it literally to help people - which is rare these days. It was late on Friday when I told Cesar that my next 2 friends would be coming, and even though it was late he went and drove to the lab to make sure that there would be stem cells available for when they had to start. You do need to heal after stem cells, and it can take some time to show up and give you all the results you need. You cannot expect instant results. But they do come, and it is worth it. Thank you to the entire Immune Regenerative Clinic - what you are doing is ground breaking and so important. I appreciate all that you have done for Julie, Roberta, Adrienne, Dave and Andres.Posted on Brendan Evans MooreheadTrustindex verifies that the original source of the review is Google. I'm glad that I chose your clinic to receive the plasmapheresis that I was seeking. Thank you nurse Aaron, Dr. Rosas, and Dr. Padilla for your attentive care. I look forward to returning to receive more services some time in the future.Posted on A YtTrustindex verifies that the original source of the review is Google. El Dr. Javier Arenas me explico detalladamente sobre las celulas madre, se tomo el tiempo de escuchar mi problema, muy profesional 100% recomendable, agradecer igualmente a Dinora Alvarez la coordinadora por haber hecho posible la comunicacion con el Dr. excelente servicio.Posted on OmarTrustindex verifies that the original source of the review is Google. I went here last week, had a wonderful experience everyone is super nice and speaks english. The doctor is very knowledgeable and does everything they can to help your situation. The facilities are extremely clean and comfortable. Every nurse I had an interaction with helped me feel comfortable and at home. I had IV, Facial, and Intrathecal. Was worried about potential side effects but suffered no negative effects. I have 0 complaints or regrets, I hope to return someday. Truly a world class experience, highly recommended.Posted on Arminda MotaTrustindex verifies that the original source of the review is Google. I was dismissed and misdiagnosed by conventional medicine for years until I found this clinic. From my first virtual consultation with Dr. Alejandra Rojas, I knew I was in the right place. She listened with care, explained everything clearly, and created a protocol tailored to my condition. Throughout treatment, she remained fully present, always responsive, precise, and supportive. Her depth of knowledge, empathy, and commitment makes her truly exceptional. The medical team, Dr. Luis Padilla, Dr. Jose Rosas, and Dr. Karla Castolo, were equally professional, kind, and focused. Their collaborative approach gave me confidence and stability at every stage. I felt safe and closely monitored the entire time. The nursing staff was outstanding. Torres and Miriam were my main nurses. Their skill and kindness made a real difference daily. Andrea and Pamela also cared for me with professionalism and warmth. Sarah, at reception, went far beyond her role. In the heat of the day, she picked up lunch for me every day just to help. She even made me a handmade necklace that deeply touched me. And on my birthday, the team surprised me with a cake. Every gesture, large or small, meant something and none of it went unnoticed. Abel, the patient coordinator, deserves special thanks. From the very first contact, his warmth and efficiency set the tone. He guided me through every detail, stayed in constant contact, and helped far beyond expectation. His presence made a lasting difference. We became true friends through the process, and I will always be grateful for his support. Lorena Shira, the clinic director, personally explained their lab protocols, ethics, and research collaboration. I was impressed by the transparency and integrity throughout. Their mesenchymal stem cells are ethically sourced and never frozen, produced in-house at their Puerto Vallarta lab under strict protocols. They operate independently and collaborate with UNAM in a national regenerative medicine initiative. I am now continuing my protocol at home with their support and follow-up. They remain fully engaged in my care, and I am hopeful for the results. This clinic is not just a medical provider. It is a place of real care, professionalism, and humanity. I received more than treatment. I will always be grateful.Posted on MARYTERESE WALLACETrustindex verifies that the original source of the review is Google. Thanks so much! Your group seem very organized. Called promptly at the scheduled time. Looking forward to the email with more info.Verified by TrustindexTrustindex verified badge is the Universal Symbol of Trust. Only the greatest companies can get the verified badge who has a review score above 4.5, based on customer reviews over the past 12 months. Read more
Frequently Asked Questions About Stem Cell Therapy for Shoulder Pain
Is stem cell therapy safe for shoulder conditions like rotator cuff tears or arthritis?
Yes. We use mesenchymal stem cells processed under strict clinical-grade conditions, following safety protocols aligned with international standards. No cryopreservation is involved—only fresh, high-viability cells are used.
How soon will I notice improvement after the procedure?
Many patients begin to notice reduced inflammation and increased mobility within a few weeks. However, regenerative processes continue developing over the following 3 to 6 months, with full benefits becoming evident over time.
Can stem cells help me avoid rotator cuff surgery?
In many cases, yes. Stem cell therapy may serve as a non-surgical alternative by promoting tissue repair, reducing pain, and improving function—especially in partial tears or early degeneration. For full-thickness tears, candidacy is determined case by case.
What’s the difference between this therapy and corticosteroid injections?
While corticosteroids temporarily suppress inflammation, stem cell therapy targets the root cause by promoting cellular repair and tissue regeneration, offering long-term improvement instead of symptom masking.
Do you combine stem cells with other regenerative therapies?
Yes. Our protocol often includes PRP (Platelet-Rich Plasma), ozone therapy, peptides, or plasmapheresis, depending on your clinical profile. These support healing, reduce oxidative stress, and enhance the effectiveness of the stem cells.
How is the procedure performed? Is it painful?
The injection is performed under image guidance (such as ultrasound or fluoroscopy) for precision. It’s a minimally invasive, outpatient procedure. Some patients report mild post-injection soreness, which typically resolves in a few days.
What’s the recovery time?
Most patients resume light activities within 2 to 5 days. Full physical therapy or athletic return-to-play timelines may vary depending on your condition and treatment plan.
How much does the treatment cost?
Treatment costs typically range between $1,900 and $5,000 USD, depending on the severity of the injury and the protocol recommended. We provide detailed, personalized cost estimates after your free medical evaluation.