Raúl Rosales Ibáñez, Ph.D.

Specialty: Dental pulp stem cells, biomaterials & scaffolds, and craniofacial tissue engineering

Dr. Raúl Rosales Ibáñez is a researcher and educator whose work centers on tissue engineering, dental pulp mesenchymal stem cells (DPSCs), and biomaterial scaffolds (e.g., PCL, PLGA, PGS, chitosan, carbon-based nanostructures) for bone and cartilage regeneration. His contributions span in-vitro and in-vivo models, electrospinning and 3D printing, surface functionalization, and safe-by-design approaches for translational craniofacial applications.

He currently serves as a full-time faculty professor at FES Iztacala, UNAM, where he teaches cellular and tissue biology, regenerative medicine and dentistry, and scientific writing, and supervises theses across undergraduate, master’s, and doctoral programs. His academic service includes doctoral committees, peer review for international journals, and participation in funded research on cleft palate regeneration and osteoinductive scaffolds.

Areas of Expertise

• Tissue engineering for bone, cartilage, and craniofacial repair
• Dental pulp stem cells (isolation, characterization, osteo/condrogenic differentiation)
• Biomaterials & scaffolds (PCL/PLGA, PGS, polyurethane, jarosite-derived and carbon nanostructures)
• Electrospinning, 3D printing, plasma and chemical surface modification
• Translational methods, preclinical models, and biocompatibility testing

Education & Training

• Ph.D. in Tissue Engineering in Medicine and Dentistry — University of Granada (2005–2008), Granada, Spain
• Specialist Diploma — Universidad Popular Autónoma del Estado de Puebla (2000–2001)
• DDS (Cirujano Dentista) — Universidad Autónoma de San Luis Potosí, Faculty of Stomatology (1991–1996)

Honors & Memberships

• Sistema Nacional de Investigadores (SNI), Mexico — Distinction granted for the periods 2018–2020 and 2021–2023
• Member, ethics and academic committees; reviewer for national and international journals

Teaching & Mentorship (selected scope)

• Undergraduate, Master’s, and Doctoral supervision and committee service in tissue engineering, biomaterials, and regenerative dentistry
• Course leadership in Cellular & Tissue Biology, Regenerative Medicine & Dentistry, Analysis of Scientific Literature, and Scientific Writing

Scientific Publications (normalized to English)

1. Multiwall Carbon Nanotubes/Polycaprolactone Scaffolds Seeded with Human Dental Pulp Stem Cells for Bone Tissue Regeneration. Journal of Materials Science: Materials in Medicine 27(2):35 (2016).
2. Development of Bioresorbable Bilayered Systems for Application as Affordable Wound Dressings. Journal of Bioactive and Compatible Polymers 31(6):624–647 (2016).
3. DPSC Colonization of Functionalized 3D Textiles. Journal of Biomedical Materials Research Part B: Applied Biomaterials (2016).
4. Strontium Folate–Loaded Biohybrid Scaffolds Seeded with Dental Pulp Stem Cells Induce In Vivo Bone Regeneration in Critical-Sized Defects. Biomaterials Science 4(11):1596–1604 (2016).
5. Improved In-Vitro Angiogenic Behavior on Anodized Titanium Dioxide Nanotubes. Journal of Nanobiotechnology 15:10 (2017).
6. Oral Mucosa: An Alternative Epidermal Cell Source to Develop Autologous Dermal–Epidermal Substitutes from Diabetic Subjects. Journal of Applied Oral Science 25(2):186–195 (2017).
7. Bioactive Sr(II)/Chitosan/Poly(ε-caprolactone) Scaffolds for Craniofacial Tissue Regeneration: In-Vitro and In-Vivo Behavior. Polymers (Basel) 10(3) (2018).
8. Preparation and Characterization of Titanium-Segmented Polyurethane Composites for Bone Tissue Engineering. Journal of Biomaterials Applications 33(1):11–22 (2018).
9. Bone Regeneration Induced by Strontium Folate–Loaded Biohybrid Scaffolds. Molecules 24(9) (2019).
10. Biomaterials for Cleft Lip and Palate Regeneration. International Journal of Molecular Sciences 20(9) (2019).
11. Titanium–Castor Oil–Based Polyurethane Composite Foams for Bone Tissue Engineering. Journal of Biomaterials Science, Polymer Edition 30(15):1419–1434 (2019).
12. Synthesis and Assessment of Poly(acrylic acid)/Polyvinylpyrrolidone Interpenetrating Network as a Matrix for Oral Mucosa Cells. Journal of Biomaterials Applications (2019).
13. Design, Synthesis, Characterization, and Cytotoxicity of PCL/PLGA Scaffolds via Plasma Treatment with Pyrrole for Possible Use in Urethral Tissue Engineering. Journal of Biomaterials Applications 34(6):840–850 (2019).
14. Tailoring Surface Properties of Carbon Nanofibers via Oxidation and Their Influence on Dental Pulp Stem Cell Viability in PCL/CNF Composites. Polymer Bulletin (2020).
15. Effect of Exposure Time on Physicochemical, Mechanical, and Biological Properties of PGS Scaffolds Treated with Iodine-Doped Polypyrrole Plasma. Journal of Biomaterials Applications (2020).
16. Relationship Between Normative Need for Orthodontic Treatment and Oral Health in Mexican Adolescents Aged 13–15 Years. International Journal of Environmental Research and Public Health 17(21):8107 (2020).
17. Lyophilized Polyvinylpyrrolidone Hydrogel for Culture of Human Oral Mucosa Stem Cells. Materials 14:227 (2021).
18. Assessment of a PCL-3D Printing–Dental Pulp Stem Cells Triplet for Bone Engineering: An In-Vitro Study. Polymers (Basel) 13(7):1154 (2021).
19. Micro-Mechanical Properties of Corneal Scaffolds from Two Bio-Models Obtained by Efficient Chemical Decellularization. Journal of the Mechanical Behavior of Biomedical Materials 119:104510 (2021).
20. Association Between Sociodemographic Factors and Non-Cavitated/Cavitated Caries Lesions in 8–12-Year-Old Mexican Schoolchildren. Medicine (Baltimore) 100(25):e26435 (2021).
21. Evaluation of the Osteoinductive Potential of HDPSCs Cultured on β-Glycerol Phosphate–Functionalized MWCNTs/PCL Membranes for Bone Regeneration. Polymer Bulletin (2021).
22. Compositions and Structural Geometries of Scaffolds Used in the Regeneration of Cleft Palates: A Literature Review. Polymers (Basel) 14(3):547 (2022).
23. Electrospun/3D-Printed PCL Bioactive Scaffold for Bone Regeneration. Polymer Bulletin (advance online/in press, 2022).
24. Doped Potassium Jarosite: Synthesis, Characterization and Evaluation as Biomaterial for Bone Tissue Engineering. Metals 12(6):1052 (2022).
25. Synthesis, Characterization and Decomposition of Potassium Jarosite for Adsorptive As(V) Removal in Contaminated Water: Preliminary Study. International Journal of Environmental Research and Public Health 19(23):15912 (2022).
26. 3D Scaffolds of Caprolactone/Chitosan/Polyvinyl Alcohol/Hydroxyapatite Stabilized by Physical Bonds Seeded with Swine Dental Pulp Stem Cells for Bone Tissue Engineering. Journal of Materials Science: Materials in Medicine 33:81 (2022).
27. Bovine Dentin Collagen/Poly(lactic acid) Scaffolds for Tooth Tissue Regeneration. Iranian Polymer Journal (2023).
28. Biological Activity of a Chitosan–Carboxymethylcellulose–Zinc Oxide and Calcium Carbonate in 3D Scaffolds Stabilized by Physical Links for Bone Tissue Engineering. Journal of Biomaterials Applications (2023).
29. In-Vitro and In-Vivo Evaluation of a PCL/PLGA (80:20) Scaffold for Improved Treatment of Chondral Injuries. Polymers (Basel) 15:2324 (2023).

Additional Indexed Publications (national & international)

• Unilateral Impact of Altered Loading by Changing Teeth Height on TMJ Fibrocartilage (Disc and Condyle) of Wistar Rats. Microscopy Research 4(2) (2016).
• Isolation, Culture, and Characterization of Bone Marrow Mesenchymal Stem Cells from New Zealand Rabbits Femur. Indexed national journal, Vol. 30 (June 2018).
• Potential Benefits from 3D Printing and Dental Pulp Stem Cells in Cleft Palate Treatments: An In-Vivo Model Study. Biomedical Journal of Scientific & Technical Research 16(2):1–4 (2019).

Books & Book Chapters

• Book: Tissue Engineering of the Temporomandibular Joint (Odontología Books, 2017), 1–159.
• Chapters: Physiology and Biomechanics of the Temporomandibular Joint (pp. 40–57, 2017); Principles of Tissue Engineering (2017).
• Preface/Introduction: Tissue Engineering of the Temporomandibular Joint (2017).