Regain Mobility and Comfort with Stem Cell Injections into the Knee
Knee pain shouldn’t stop you from living fully. Our advanced stem cell therapy for knees helps regenerate cartilage, reduce inflammation, and restore joint function—without the need for invasive surgery or long recovery times. Whether you’re dealing with arthritis, meniscus damage, or chronic joint pain, this treatment offers a powerful, science-backed alternative to knee replacement.
¿Qué es la artritis reumatoide y cómo afecta tu vida?
Cortisone injections, painkillers, and even surgery are common solutions for knee pain. But most of these options only address symptoms—temporarily. They don’t reverse the damage, and in many cases, they lead to more complications or ongoing dependency on medication.
Cortisone and NSAIDs
These treatments may reduce inflammation in the short term, but they don’t help regenerate tissue. Over time, they can even weaken cartilage and worsen joint degeneration.
Knee Replacement Surgery
While sometimes necessary, knee replacement is a major surgery with high cost, risk of complications, and long recovery time. Many patients also report limitations in mobility even after recovery.
Physical Therapy Alone
Physical therapy is important, but without addressing the underlying tissue damage, it often has limited long-term impact for those with moderate to severe joint degeneration.
That’s where regenerative medicine—and specifically stem cell injections into the knee—offers a transformative alternative. Instead of masking pain, we focus on healing the joint from within.

How Stem Cell Therapy Helps Rebuild Your Knee Joint
Unlike traditional treatments that only manage symptoms, stem cell injections into the knee target the root cause—damaged cartilage and chronic inflammation. Our protocol supports tissue regeneration, pain relief, and joint function restoration through advanced cellular techniques.
Cartilage Regeneration
MSCs support the regeneration of hyaline cartilage, which is often worn down in patients with knee osteoarthritis or past injuries.
Anti-Inflammatory Effect
Stem cells naturally regulate inflammatory responses, reducing swelling, stiffness, and joint pain over time.
Protection from Further Degeneration
By improving the joint environment, stem cells can slow the progression of arthritis and protect the remaining cartilage from further damage.
Improved Joint Function & Mobility
Patients typically experience increased range of motion and reduced pain during walking, bending, and everyday activities.
In-Clinic Procedure: What to Expect
At Immunotherapy Regenerative Medicine, our stem cell therapy protocol for knees is performed with precision and care, using mesenchymal stem cells (MSCs) and platelet-rich plasma (PRP) to promote optimal joint regeneration. The procedure is minimally invasive and designed for international patients seeking effective, safe, and medically advanced alternatives to knee surgery.
1. Personalized Medical Assessment
We begin with a full evaluation of your condition—reviewing imaging (MRI or X-ray), mobility limitations, and symptoms. This step ensures that your treatment plan is tailored specifically to your needs.
2. Stem Cell & PRP Preparation in Our Lab
Our team cultivates fresh mesenchymal stem cells in a certified lab under strict quality protocols. These cells, combined with your own PRP, enhance regeneration and accelerate healing. We never use frozen or low-viability cells.
3. Combined Regenerative Therapies
Depending on your case, your protocol may include ozone therapy, plasmapheresis, IV nutrient support, and peptides to optimize outcomes and systemic recovery.
4. Post-Treatment and Recovery
Most patients resume normal activities within 2 to 7 days, depending on their response and baseline health. We provide ongoing follow-up and support to monitor your progress and guide your recovery.
Why Patients Choose Our Knee Regenerative Program
Patients from around the world trust our advanced knee therapy program for its scientific foundation, clinical integrity, and personalized care. At Immunotherapy Regenerative Medicine, we don’t just treat pain—we restore mobility, function, and quality of life through evidence-based regenerative protocols.
Más de 20 años de experiencia médica
Hemos sido pioneros en medicina regenerativa e integrativa durante más de dos décadas, liderados por un equipo de médicos, científicos y especialistas clínicos.
Laboratorio propio de última generación
Contamos con un laboratorio interno que produce células madre mesenquimales de alta viabilidad (97–99%), bajo estrictos controles de calidad que garantizan seguridad, potencia y consistencia en cada tratamiento.
Terapias integrales y multimodales
Combinamos células madre, exosomas, péptidos, ozonoterapia y estrategias de desintoxicación para actuar en múltiples vías terapéuticas y lograr un beneficio clínico máximo.
Atención integral al paciente
Desde la evaluación inicial hasta el seguimiento a largo plazo, acompañamos tu proceso de sanación en cada etapa con soporte médico, emocional y logístico.
Protocolos verdaderamente personalizados
Cada protocolo se diseña de forma individual, basado en tu biología, objetivos y antecedentes médicos — sin plantillas, sin atajos. Solo atención de precisión basada en ciencia.
Confiado por pacientes de todo el mundo
Recibimos pacientes internacionales que buscan terapias celulares seguras, éticas y respaldadas por la ciencia.
Regulados y transparentes
Cumplimos con normativas estrictas de seguridad alineadas con COFEPRIS y estándares equivalentes a la FDA, garantizando ética médica, transparencia y calidad.
Asistencia concierge para pacientes internacionales
Our international concierge team offers guidance on ground transportation, lodging options, laboratory coordination, and general assistance throughout your visit.
La experiencia de nuestros pacientes
Paul Coffey2023-02-05Trustindex verifies that the original source of the review is Google. My wife and I visited the clinic for 10 days in July last year. The treatment that my wife received was very professional and so very friendly. I have no negatives about Immunotherapy Regenerative Medicine. All the medical staff from nurses to doctors gave the utmost professional care. From our pick up from the airport by one of the nicest guys I have ever met and am now pleased to call a friend, Diego made us feel at ease from the start. He’s very informative about all the procedures and he’s always there to check up on how you’re going. He goes above and beyond to make sure you’re happy and comfortable. Caesar is also one of the most helpful and informative members of the staff. He also would go would go above and beyond to help you in any way he could. He has also become a friend. I can’t wait to come back and have a catch up. Thank you to everyone there. I love you all. Dawn Gibson2022-12-21Trustindex verifies that the original source of the review is Google. I had stem cell injections in both my knees a week ago. The clinic itself is clean, modern and very comfortable. The staff who attended to me from consultation to injection day (Diego, Lorena, Dr. Manuel Rosas and the 2 nurses) were informative, professional, attentive and very caring. I was shown cells, plasma, etc beforehand and every procedure explained in detail prior to Dr. Rosas carrying them out. The aftercare texts on whatsapp have been fabulous and have put my mind at ease as to what to expect and when. Every question before my treatment and after has been answered promptly and truthfully. I would recommend this clinic to anyone seeking stem cell therapy as an alternative to surgery. I'm just hoping and praying the stem cells do their work and I can avoid nasty knee replacement surgery back home. Charmagne Bagley2022-11-27Trustindex verifies that the original source of the review is Google. Working with Diego Hernandez, as well as the team of medical providers and support staff made some of the challenges of our trip so much easier than it could’ve been. Prior to Diego meeting us, he was 110% vested in our best outcome. There were several challenges along the way with travel setback’s, including the recent earthquake that hit PV the day we arrived. They were never unwavering in their support and accommodations of services they provided to us. I am a young 61 1/2 year-old who has been battling chronic pain and PTSD for decades, as well as in need of Bi-lateral knee replacements. The compassion and support provided to myself and family while we were there receiving treatment was very appreciated. I felt like we were in the company of longtime friends. Diego went above and beyond in any way he could to make certain that we received all of our services as seamlessly as possible. I am pleased with the outcomes so far, though I did not expect some of the very noticeable improvements with regard to my brain healing after having had multiple viruses this past year and traumatic events. Diego was instrumental in helping me select, the treatment that would be best suited for my complex medical history which was pretty lengthy. He was very patient in reading through, and sensitive coordinating with the physicians for my best interest. I have recommended this Team & facility to several other patients in the US. I am now hopeful as I’m looking forward to the future benefits Diego helped me select for my treatment. In the process Diego has become a valued friend. I am so grateful and blessed to be feeling relief after decades of Chronic Pain, PTSD, arthritis and compromised immune system as I’m seeing and documenting my improvements over the past eight weeks. Thank you all ♥️ Gracias Sheila Pierce2022-11-01Trustindex verifies that the original source of the review is Google. I can't thank the clinic staff enough! They are caring and considerate members of my health care team now. I was seen 3 weeks ago and have experienced noticeable improvements in my health since then. I am already in contact with them regarding my next visit. Deborah Dore2022-09-24Trustindex verifies that the original source of the review is Google. Dr Romero is on the cutting edge of stem cell therapies and is known around the world for his comprehensive research and therapy applications. He along with his team of doctors, nurses and staff are professional, warm, and knowledgeable and provide a clean comfortable clinic for healing. I cannot say enough about the constant care and attention I received. I felt the results immediately and can see amazing results in the family members that received therapy with me. Joanna Sullivan2022-07-09Trustindex verifies that the original source of the review is Google. This clinic surpassed all my hopes, dreams and expectations. All the staff were happy relaxed and absolutely nothing was too much trouble. Diego, who was my first contact with immunotherapy regenerative medicine, not only delivered everything and more that was quoted by the facility, but picked me up from the airport, checked on me daily, explained daily treatments, scheduled all my treatments and provided me with his personal number for 24 hour support. He is completely trustworthy and genuine and will give you an honest prognosis. Cesar, one of the drivers and another patient intermediary was also always happy and helpful and great at explaining procedures and after care. Again, nothing was ever too much trouble. Dr. Romeo, founder and owner of the clinic, is one of the most knowledgeable men in the field of stems cells. He works tirelessly to find the protocol that is going to have the best results for your condition. His laboratory makes its own stem cells and I believe has one of the highest concentration of living stem cells of any treatment available in the world. The other doctors, personally trained by Romeos were also incredibly knowledgeable and helpful. The nurses were so kind, gentle and caring and they could all put in an IV first go!!! A little pinch but never a bruise. The clinic also offers many other treatments. Beauty treatments, dental, plastic surgery, clinics and many others. I was very happy with my dental visit with the lovely and incredibly gentle Dr Rojas, had an ozone colonic which was awesome and prp and stem cell facial infusion from which I saw immediate anti aging results. I will definitely be back again in the future, not to mention that Puerto Vallarta is a beautiful holiday destination with loads of great tourist sites to be experienced. And the clinic is located at the beautiful Marina. If you have a degenerative disease, cancer, osteoarthritis (like me) or just value your health and well being and want to age as pain free as possible then you have absolutely nothing to lose and everything to gain by visiting immunoregenerative therapy ASAP. Cathy Kornegay2022-06-19Trustindex verifies that the original source of the review is Google. Superior! The excellent quality of care, knowledge, compassion and respect that I received from all staff members made me feel completely comfortable. They rate far above any medical service I have experienced in the United States. Having had 4 substandard treatments for RA in Panama and my health not improving, I researched to find the doctors at Immunotherapy Regenerative Medicine, who are in the business for all the right reasons. Credits to Diego, the company liaison, who excels in all aspects, for exceptional attention in making the experience as easy as being with family. They prepared me so the stem cells would be most effective and I am happy to report that I am feeling better today than I have since well before being diagnosed. They are the best and I trust them with my life! You should too. Chris Campabello2022-01-31Trustindex verifies that the original source of the review is Google. Wow! Light years ahead of USA in alt therapies. Amazing service and never a rushed impatient feeling from all our questions! Professional and pleasant staff! Beautiful CLEAN facilities! Whether you are trying to treat an ailment or just reducing toxin load, one really can’t beat their protocols! Thank you for the positive quality of life extension!Verified by TrustindexTrustindex verified badge is the Universal Symbol of Trust. Only the greatest companies can get the verified badge who has a review score above 4.5, based on customer reviews over the past 12 months. Read more
Preguntas Frecuentes
Are stem cell injections into the knee safe?
Sí. Nuestros tratamientos utilizan células madre mesenquimales procesadas en nuestro laboratorio interno certificado, bajo estrictos protocolos de seguridad y calidad. Seguimos normativas internacionales (incluyendo COFEPRIS) y hemos tratado a numerosos pacientes sin efectos secundarios mayores.
How long does the procedure take?
The knee injection is performed on the same day, and the full anti-inflammatory and regenerative protocol typically spans 7 to 10 days. Most patients return to normal activities within 2 to 7 days after the procedure.
What types of knee conditions can this therapy treat?
We treat knee osteoarthritis, meniscus tears, ligament injuries, cartilage damage, and chronic pain. It’s also used as an alternative to or preparation for knee replacement surgery.
Are the results long-lasting?
Results depend on individual factors, but many patients experience significant relief and functional improvement lasting 12 to 24 months or longer, especially when combined with lifestyle and physical therapy.
Can this therapy help me avoid surgery?
In many cases, yes. Stem cell therapy is often chosen by patients looking to delay or avoid surgery, especially knee replacement or arthroscopy.
What’s the success rate?
Based on clinical data and patient outcomes, 70–90% of individuals report improved mobility, reduced inflammation, and less pain after undergoing the full protocol.
How much do stem cell knee injections cost in Mexico?
Our knee-focused regenerative treatment ranges between $1,900 and $5,000 USD, depending on case complexity and therapy combination (PRP, IV support, etc.). A personalized evaluation is required.