Non-Surgical Stem Cell Therapy for Shoulder Pain & Rotator Cuff Injuries
Struggling with shoulder pain, limited mobility, or a torn rotator cuff? Discover a regenerative, minimally invasive alternative designed to repair tissue, reduce inflammation, and help you regain full range of motion — without surgery.
- Targets shoulder arthritis, labral tears, and rotator cuff injuries
- Image-guided injections with mesenchymal stem cells and PRP
- Faster recovery with no hospital stay required
Understanding Shoulder Pain & Rotator Cuff Injuries
The shoulder is one of the most mobile and complex joints in the human body — and also one of the most vulnerable to injury. Whether caused by wear and tear, trauma, or overuse, conditions such as rotator cuff tears, labral injuries, tendonitis, and shoulder arthritis can severely impact mobility and quality of life.
When the soft tissues surrounding the shoulder joint become damaged or inflamed, patients often experience:
Persistent pain (especially when lifting or sleeping on the side)
Limited range of motion
Weakness in the arm and shoulder
Clicking or catching sensations
Difficulty performing everyday tasks
Traditional treatments like corticosteroid injections or surgery may provide temporary relief, but they often fail to repair the underlying damage — and in many cases, involve long recovery times.
How Stem Cell Therapy Helps Restore Shoulder Function
Stem cell therapy offers a minimally invasive, regenerative alternative to shoulder surgery — especially for individuals with rotator cuff tears, labral injuries, or arthritis-related degeneration.
Our protocol uses mesenchymal stem cells (MSCs), known for their ability to:
Reduce inflammation
MSCs modulate the immune response to calm chronic inflammation, a key cause of shoulder joint deterioration.
Promote tissue regeneration
They stimulate the repair of damaged tendons, cartilage, and joint structures — helping restore strength and mobility.
Support collagen synthesis
Essential for repairing rotator cuff and labral tissues, especially in partial or moderate tears.
Improve circulation and healing environment
When combined with PRP (Platelet-Rich Plasma), the therapy boosts the regenerative potential and speeds recovery.
Step-by-Step: Your Personalized Stem Cell Shoulder Treatment
Our protocol is designed to treat not just symptoms — but the root cause of shoulder pain and dysfunction. Here’s what your personalized regenerative journey looks like:
1. Initial Consultation & Medical Evaluation
We start with an in-depth clinical and imaging assessment. Our medical team evaluates the condition of your shoulder (rotator cuff, labrum, joint cartilage, etc.) to determine if you’re a good candidate.
2. Personalized Regenerative Protocol
Once approved, we design a treatment plan tailored to your condition, age, activity level, and medical history.
Our protocol may include:
Células madre mesenquimales (MSC) cultured in our in-house lab
Platelet-Rich Plasma (PRP) to enhance regenerative signaling
Ozonoterapia to improve oxygenation and anti-inflammatory response
IV peptide therapy and micronutrient support for systemic rejuvenation
3. Precise Stem Cell Injection Under Imaging Guidance
The MSCs are injected directly into the damaged shoulder structures using real-time imaging (ultrasound or fluoroscopy). This ensures high accuracy and maximizes therapeutic potential.
The procedure is minimally invasive, performed in a sterile environment, and typically takes less than 90 minutes.
4. Recovery and Follow-Up Support
There is no hospitalization or general anesthesia required. Most patients resume daily activities within 3 to 7 days.
Our team monitors your progress and adjusts your recovery plan as needed.
Follow-ups may include mobility assessments, nutritional guidance, and optional supportive therapies like PRP boosters or additional IV sessions.

Why Does Shoulder Pain Occur?
The shoulder is one of the most versatile joints in the body, making it prone to wear and tear over time. Conditions such as arthritis, rotator cuff injuries, and ligament tears can lead to chronic pain and limited mobility.
Common Causes of Shoulder Pain
- Shoulder Arthritis: Degenerative joint disease causes cartilage breakdown, leading to pain and stiffness.
- Rotator Cuff Injuries: Tears or inflammation in the tendons affect the joint’s stability and function.
- Labral Tears: Damage to the cartilage ring supporting the shoulder joint results in discomfort and instability.
Traditional treatments like physical therapy or surgery often fall short in addressing the root cause of the problem. This is where stem cell injections for shoulders come in, offering a regenerative approach to healing.
Why Patients Choose Our Stem Cell Shoulder Program
At Immunotherapy Regenerative Medicine, we don’t just treat shoulder pain — we treat people.
Our approach blends scientific rigor, personalized care, and over 20 years of clinical experience to deliver results that matter.
Discover what sets us apart through these key advantages:
Más de 20 años de experiencia médica
Nuestra clínica ha sido pionera en medicina regenerativa por más de dos décadas, liderada por un equipo de especialistas con amplia trayectoria.
Laboratorio propio de última generación
Procesamos nuestras propias células madre mesenquimales de alta viabilidad (98–99%), lo que garantiza seguridad, consistencia y calidad superior.
Terapias integrales y multimodales
Combinamos infusiones de células madre, inyecciones intratecales, exosomas, péptidos y terapias de desintoxicación para lograr un mayor impacto terapéutico.
Atención integral al paciente
Desde la evaluación inicial hasta el seguimiento a largo plazo, nuestro equipo te acompaña en cada etapa de tu proceso de sanación.
Protocolos personalizados para cada paciente
Cada tratamiento se diseña de forma individualizada, según tu condición, historial médico y objetivos, para asegurar el máximo beneficio.
Reputación global y confianza de los pacientes
Recibimos pacientes de todo el mundo que buscan terapias celulares avanzadas, seguras y respaldadas por evidencia científica.
Regulación y transparencia garantizadas
Seguimos estrictos estándares internacionales de seguridad, alineados con COFEPRIS y normativas equivalentes a la FDA.
Servicio concierge para pacientes internacionales
Coordinamos tu viaje de forma fluida: apoyo local, transporte, recomendaciones de alojamiento y asistencia personalizada durante tu estancia.
La experiencia de nuestros pacientes
Paul Coffey2023-02-05Trustindex verifies that the original source of the review is Google. My wife and I visited the clinic for 10 days in July last year. The treatment that my wife received was very professional and so very friendly. I have no negatives about Immunotherapy Regenerative Medicine. All the medical staff from nurses to doctors gave the utmost professional care. From our pick up from the airport by one of the nicest guys I have ever met and am now pleased to call a friend, Diego made us feel at ease from the start. He’s very informative about all the procedures and he’s always there to check up on how you’re going. He goes above and beyond to make sure you’re happy and comfortable. Caesar is also one of the most helpful and informative members of the staff. He also would go would go above and beyond to help you in any way he could. He has also become a friend. I can’t wait to come back and have a catch up. Thank you to everyone there. I love you all. Dawn Gibson2022-12-21Trustindex verifies that the original source of the review is Google. I had stem cell injections in both my knees a week ago. The clinic itself is clean, modern and very comfortable. The staff who attended to me from consultation to injection day (Diego, Lorena, Dr. Manuel Rosas and the 2 nurses) were informative, professional, attentive and very caring. I was shown cells, plasma, etc beforehand and every procedure explained in detail prior to Dr. Rosas carrying them out. The aftercare texts on whatsapp have been fabulous and have put my mind at ease as to what to expect and when. Every question before my treatment and after has been answered promptly and truthfully. I would recommend this clinic to anyone seeking stem cell therapy as an alternative to surgery. I'm just hoping and praying the stem cells do their work and I can avoid nasty knee replacement surgery back home. Charmagne Bagley2022-11-27Trustindex verifies that the original source of the review is Google. Working with Diego Hernandez, as well as the team of medical providers and support staff made some of the challenges of our trip so much easier than it could’ve been. Prior to Diego meeting us, he was 110% vested in our best outcome. There were several challenges along the way with travel setback’s, including the recent earthquake that hit PV the day we arrived. They were never unwavering in their support and accommodations of services they provided to us. I am a young 61 1/2 year-old who has been battling chronic pain and PTSD for decades, as well as in need of Bi-lateral knee replacements. The compassion and support provided to myself and family while we were there receiving treatment was very appreciated. I felt like we were in the company of longtime friends. Diego went above and beyond in any way he could to make certain that we received all of our services as seamlessly as possible. I am pleased with the outcomes so far, though I did not expect some of the very noticeable improvements with regard to my brain healing after having had multiple viruses this past year and traumatic events. Diego was instrumental in helping me select, the treatment that would be best suited for my complex medical history which was pretty lengthy. He was very patient in reading through, and sensitive coordinating with the physicians for my best interest. I have recommended this Team & facility to several other patients in the US. I am now hopeful as I’m looking forward to the future benefits Diego helped me select for my treatment. In the process Diego has become a valued friend. I am so grateful and blessed to be feeling relief after decades of Chronic Pain, PTSD, arthritis and compromised immune system as I’m seeing and documenting my improvements over the past eight weeks. Thank you all ♥️ Gracias Sheila Pierce2022-11-01Trustindex verifies that the original source of the review is Google. I can't thank the clinic staff enough! They are caring and considerate members of my health care team now. I was seen 3 weeks ago and have experienced noticeable improvements in my health since then. I am already in contact with them regarding my next visit. Deborah Dore2022-09-24Trustindex verifies that the original source of the review is Google. Dr Romero is on the cutting edge of stem cell therapies and is known around the world for his comprehensive research and therapy applications. He along with his team of doctors, nurses and staff are professional, warm, and knowledgeable and provide a clean comfortable clinic for healing. I cannot say enough about the constant care and attention I received. I felt the results immediately and can see amazing results in the family members that received therapy with me. Joanna Sullivan2022-07-09Trustindex verifies that the original source of the review is Google. This clinic surpassed all my hopes, dreams and expectations. All the staff were happy relaxed and absolutely nothing was too much trouble. Diego, who was my first contact with immunotherapy regenerative medicine, not only delivered everything and more that was quoted by the facility, but picked me up from the airport, checked on me daily, explained daily treatments, scheduled all my treatments and provided me with his personal number for 24 hour support. He is completely trustworthy and genuine and will give you an honest prognosis. Cesar, one of the drivers and another patient intermediary was also always happy and helpful and great at explaining procedures and after care. Again, nothing was ever too much trouble. Dr. Romeo, founder and owner of the clinic, is one of the most knowledgeable men in the field of stems cells. He works tirelessly to find the protocol that is going to have the best results for your condition. His laboratory makes its own stem cells and I believe has one of the highest concentration of living stem cells of any treatment available in the world. The other doctors, personally trained by Romeos were also incredibly knowledgeable and helpful. The nurses were so kind, gentle and caring and they could all put in an IV first go!!! A little pinch but never a bruise. The clinic also offers many other treatments. Beauty treatments, dental, plastic surgery, clinics and many others. I was very happy with my dental visit with the lovely and incredibly gentle Dr Rojas, had an ozone colonic which was awesome and prp and stem cell facial infusion from which I saw immediate anti aging results. I will definitely be back again in the future, not to mention that Puerto Vallarta is a beautiful holiday destination with loads of great tourist sites to be experienced. And the clinic is located at the beautiful Marina. If you have a degenerative disease, cancer, osteoarthritis (like me) or just value your health and well being and want to age as pain free as possible then you have absolutely nothing to lose and everything to gain by visiting immunoregenerative therapy ASAP. Cathy Kornegay2022-06-19Trustindex verifies that the original source of the review is Google. Superior! The excellent quality of care, knowledge, compassion and respect that I received from all staff members made me feel completely comfortable. They rate far above any medical service I have experienced in the United States. Having had 4 substandard treatments for RA in Panama and my health not improving, I researched to find the doctors at Immunotherapy Regenerative Medicine, who are in the business for all the right reasons. Credits to Diego, the company liaison, who excels in all aspects, for exceptional attention in making the experience as easy as being with family. They prepared me so the stem cells would be most effective and I am happy to report that I am feeling better today than I have since well before being diagnosed. They are the best and I trust them with my life! You should too. Chris Campabello2022-01-31Trustindex verifies that the original source of the review is Google. Wow! Light years ahead of USA in alt therapies. Amazing service and never a rushed impatient feeling from all our questions! Professional and pleasant staff! Beautiful CLEAN facilities! Whether you are trying to treat an ailment or just reducing toxin load, one really can’t beat their protocols! Thank you for the positive quality of life extension!Verified by TrustindexTrustindex verified badge is the Universal Symbol of Trust. Only the greatest companies can get the verified badge who has a review score above 4.5, based on customer reviews over the past 12 months. Read more
Frequently Asked Questions About Stem Cell Therapy for Shoulder Pain
Is stem cell therapy safe for shoulder conditions like rotator cuff tears or arthritis?
Yes. We use mesenchymal stem cells processed under strict clinical-grade conditions, following safety protocols aligned with international standards. No cryopreservation is involved—only fresh, high-viability cells are used.
How soon will I notice improvement after the procedure?
Many patients begin to notice reduced inflammation and increased mobility within a few weeks. However, regenerative processes continue developing over the following 3 to 6 months, with full benefits becoming evident over time.
Can stem cells help me avoid rotator cuff surgery?
In many cases, yes. Stem cell therapy may serve as a non-surgical alternative by promoting tissue repair, reducing pain, and improving function—especially in partial tears or early degeneration. For full-thickness tears, candidacy is determined case by case.
What’s the difference between this therapy and corticosteroid injections?
While corticosteroids temporarily suppress inflammation, stem cell therapy targets the root cause by promoting cellular repair and tissue regeneration, offering long-term improvement instead of symptom masking.
Do you combine stem cells with other regenerative therapies?
Yes. Our protocol often includes PRP (Platelet-Rich Plasma), ozone therapy, peptides, or plasmaféresis, depending on your clinical profile. These support healing, reduce oxidative stress, and enhance the effectiveness of the stem cells.
How is the procedure performed? Is it painful?
The injection is performed under image guidance (such as ultrasound or fluoroscopy) for precision. It’s a minimally invasive, outpatient procedure. Some patients report mild post-injection soreness, which typically resolves in a few days.
What’s the recovery time?
Most patients resume light activities within 2 to 5 days. Full physical therapy or athletic return-to-play timelines may vary depending on your condition and treatment plan.
¿Cuál es el costo del tratamiento?
Treatment costs typically range between $1,900 and $5,000 USD, depending on the severity of the injury and the protocol recommended. We provide detailed, personalized cost estimates after your free medical evaluation.